All the Covid-19 vaccines have probably taken “some hit” in terms of efficacy with the variants, and that’s why its urgent that vaccinations happen as fast as possible said Dr. Linda-Gail Bekker, deputy director of the Desmond Tutu HIV Centre at the University of Cape Town in South Africa.
“The message has to be, let’s vaccinate while we’ve got a window of opportunity and a vaccine, several vaccines, that work against the current virus,” Bekker said at the International AIDS Society Monday.
Trials in South Africa show that the Johnson & Johnson vaccine does seem to provide protection against the variants there, even if it is slightly diminished protection. It provided 57% protection against moderate disease in South Africa, compared to the US where it provided 72% protection, according to J&J. But globally it provided 85% protection against severe disease.
The mRNA vaccines from Pfizer and Moderna are still being tested to see how they protect people from the variants, with more than 90% efficacy in clinical trials against the original virus, Bekker said, there is “a lot of headroom.”
“Even if there is a little bit of a ding there, we will still be in a very good space in terms of efficaciousness,” Bekker said.
“Vaccine impact is a mixture of efficacy and coverage. So what we take away from this is, if we give up a little bit of efficacy because we have a mutation to deal with, then we have to be sure to get that coverage out even more,” Bekker said. “That really just spurs us on to the urgency to get the vaccine out there as quickly as possible.”