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This webinar features Solve Ramsay Research Grant winners Liisa K. Selin, MD, PhD, Anna Gil, PhD (viral immunologists from the Univ. of Massachusetts Chan Medical School), Roshan Kumar, PhD (clinical stage global biotech company HiFiBiO Therapeutics), and the labs’ patient representatives Megan L. Fitzgerald, PhD, and Rivka Solomon, MS.
These two collaborating labs are studying dysregulated immune cells of ME/CFS and Long COVID patients. Their research goals include: gaining insights into the underlying immune mechanisms of these illnesses (including via antigen discovery); better understanding patient subgroups; and finding diagnostic biomarkers and therapeutic innovations.
The two labs received funding from the Patient Led Research Collaborative to collaborate on their current project analyzing T cells from ME/CFS and Long COVID patients both functionally and at a single-cell level.
Also at this webinar moderated by Solve CEO Emily Taylor, …...more
Immune Dysfunction & T-Cell Exhaustion via Single Cell Immune Profiling in ME/CFS & Long COVID
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2,338Views
Apr 302025
This webinar features Solve Ramsay Research Grant winners Liisa K. Selin, MD, PhD, Anna Gil, PhD (viral immunologists from the Univ. of Massachusetts Chan Medical School), Roshan Kumar, PhD (clinical stage global biotech company HiFiBiO Therapeutics), and the labs’ patient representatives Megan L. Fitzgerald, PhD, and Rivka Solomon, MS.
These two collaborating labs are studying dysregulated immune cells of ME/CFS and Long COVID patients. Their research goals include: gaining insights into the underlying immune mechanisms of these illnesses (including via antigen discovery); better understanding patient subgroups; and finding diagnostic biomarkers and therapeutic innovations.
The two labs received funding from the Patient Led Research Collaborative to collaborate on their current project analyzing T cells from ME/CFS and Long COVID patients both functionally and at a single-cell level.
Also at this webinar moderated by Solve CEO Emily Taylor, the Selin Lab summarizes its paper “Identification of CD8 T-cell dysfunction associated with symptoms in ME/CFS and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series.”
The webinar covers complex scientific information, and our panelists have kindly provided a layperson-friendly summary of the material below. It describes the defects these investigators (Selin Lab and HiFiBiO Therapeutics) have found in cells of the immune system from people with ME/CFS and Long COVID. They believe these defects are at the core of ME/CFS and Long COVID.
https://solvecfs.org/a-guide-to-inves...…...more
