Today, our partner CARB-X published their annual report that highlights continued efforts accelerating early-stage antibacterial candidates into clinical development to help fill strategic gaps in the antimicrobial resistance (AMR) medical countermeasures pipeline. The report showcases project milestones, new funding commitments, upcoming funding rounds, and Portfolio Acceleration Tools. As a founding funder of the CARB-X global accelerator, BARDA is dedicated to advancing novel and innovative medical countermeasures to help combat the threat of drug-resistant infections and increase the USG’s preparedness posture. To read more about the progress achieved by CARB-X developers over the past year, visit https://lnkd.in/e27JjCn Learn more about our partnership with CARB-X and how we are working together to address AMR: https://lnkd.in/dSW3vwvP
📣 PUBLISHED TODAY: CARB-X’s 2023 Annual Report is out! The report highlights key takeaways from the portfolio strategy review, funding round results, our work in low- and middle-income countries (LMICs), new CARB-X funders the Government of Canada and the Novo Nordisk Foundation as well as renewed funding from UK Health Security Agency and Bundesministerium für Bildung und Forschung. 2023 saw the close of CARB-X’s Omnibus Funding Round focused on three themes: oral therapeutics, vaccines for neonatal sepsis and gonorrhea products. CARB-X received 237 Expressions of Interest from 185 unique applicants around the world. Several trends emerged, including: 👉 Rapid diagnostics expanded during the COVID-19 pandemic, leaving product developers poised to capitalize on their investments by embracing new sample types and pathogens. 👉 Half of therapeutics applicants were in the hit-to-lead stage, reinforcing the evident dearth of oral therapeutics in the clinical and preclinical pipelines. 👉 CARB-X received Expressions of Interest from the vaccine community in response to the lack of vaccines in development for K. pneumoniae, Extraintestinal Pathogenic E. coli, S. aureus, A baumannii, and N. gonorrhoeae. “With a shared vision of a healthier future for all, we look forward to continuing our work with partners in the antibacterial innovation chain to close this gap and bring innovative tools to everyone who needs them,” said Kevin Outterson, Executive Director of CARB-X and Austin B. Fletcher Professor of Law at Boston University. 🔗 Read more: bit.ly/49YZjOx Thank you to our funders: Boston University School of Law Boston University Biomedical Advanced Research and Development Authority (BARDA) HHS Administration for Strategic Preparedness and Response National Institute of Allergy and Infectious Diseases (NIAID) Wellcome Trust UK Health Security Agency Department of Health and Social Care Bundesministerium für Bildung und Forschung Bill & Melinda Gates Foundation Government of Canada and Novo Nordisk Foundation