So, during this meeting, I presented the preliminary results of the VENTOGRAFT study. It’s a study from the French group of myelodysplasia. The aim of the study was to evaluate the combination of azacitidine plus venetoclax plus donor lymphocyte infusion in patients in relapse after allo stem cell transplantation for MDS and AML. So, in this presentation, I presented the preliminary results from the Phase I...
So, during this meeting, I presented the preliminary results of the VENTOGRAFT study. It’s a study from the French group of myelodysplasia. The aim of the study was to evaluate the combination of azacitidine plus venetoclax plus donor lymphocyte infusion in patients in relapse after allo stem cell transplantation for MDS and AML. So, in this presentation, I presented the preliminary results from the Phase I. In this Phase I, there were three dose levels. So for venetoclax: venetoclax 100mg per day for 14 days, venetoclax 200mg per day for 14 days, and the last level was venetoclax of 400mg per day for 14 days. During this Phase I, we observed only one DLT at dose level three. So, we need to include three more patients. So, for the moment, we have finished the Phase I part, so 12 patients were included in this clinical trial, and we could define the MTD for the Phase II part. So the MTD was the level three, so 400mg per day for 14 days. And the preliminary results show very promising results with an overall response rate of 67%. For the moment, of course, we have no survival data, but it’s really encouraging in this very poor patient [population].