Quality control of cell lines used in biomedical research is essential to ensure reproducibility. Although cell line authentication has been widely recommended for many years, misidentification, including cross-contamination, remains a serious problem. We outline a multi-stakeholder, incremental approach and policy-related recommendations to facilitate change in the culture of cell line authentication.
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The authors thank the Global Biological Standards Institute staff for support during the preparation of this paper.
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Freedman, L., Gibson, M., Ethier, S. et al. Reproducibility: changing the policies and culture of cell line authentication. Nat Methods 12, 493–497 (2015). https://doi.org/10.1038/nmeth.3403
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DOI: https://doi.org/10.1038/nmeth.3403
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