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High-Resolution Metabolic and Behavioral Phenotyping Systems for Rodents
Promethion Core® is the only metabolic and behavioral phenotyping system that enables the tight synchronization of metabolic data with behavioral events. This is made possible by our exclusive SableHD™ high-definition digital technology, providing you with industry-leading accuracy, highest sampling rate, and unbeatable resolution of rapidly changing metabolic data. You will see every aspect of metabolism and behavior more clearly, with finer detail, quality, and repeatability—giving you complete confidence in your data.
Promethion Core systems are typically comprised of 8 to 16 rat or mouse cages, independent mass flow controllers, analyzers, pumps, and Promethion Live software platform. The combined gas analyzers and flow regulation (CGF) module is mounted to the side of the environmental cabinet or rack, minimizing footprint while neatly organizing tubes and cords. Efficient system management is at the heart of Promethion Core’s innovative design and enables technicians to easily manage animals and maintain the cages.
Sable offers several Promethion Core system configurations to meet a wide range of research needs.
MOUSE SYSTEMS
Rat SYSTEMS
SEE WHAT OTHERS MISS
Temporal Resolution Comparison: Promethion Core vs. Other Systems
Promethion Core: Fast Response for Synchronized Results
Promethion Core multiplexed system allows you to realize the full benefit of high resolution performance. The data above shows the synchronization of activity with energy expenditure. The EE graph shows sharp peaks and stable baselines enabling accurate active and resting energy expenditure calculation.
Competitor’s System:
Slow, Blurred Response
Competitors’ continuous systems limit your research capabilities by using old, low resolution technology. The graph above shows broad peaks and no baseline. Therefore, the energy expenditure values are inaccurate.
REAL-TIME SOFTWARE PLATFORM OPTIMIZED FOR RESEARCHERS
The Promethion Live™ software platform maximizes experiment success by verifying system performance and simplifying setup. One-step gas calibration ensures accurate respirometry measurements. User selectable configuration options are system specific. Status indicators of vital components verifies system performance. Routine experiment configurations are simply saved and simply reused. Smart setup delivers reliable experiments so that you can proceed with confidence.
Actionable Intelligence
Promethion Live empowers you with real time animal and system information needed to make key decisions at any time and from any place. You’ll have immediate access to the health and welfare information for each animal. By monitoring activity, ingestive behavior and weight change, you will know when to adjust parameters.
Real Time Experiment Evaluation
Now you can explore comparative trends during an experiment looking at every facet measured, such as running activity, food consumption, or energy expended (data shown). The experiment result is no longer a black box to be opened at the end. Promethion Live provides the mean or median of grouped data for statistical comparison in real time. The data may be presented in real time or extracted for further evaluation.
SUPERIOR CAGE TECHNOLOGY
Cage configurations can include food, water, and body mass, running wheel and activity detection monitors, food access control, telemetry, as well as access port capability for optogenetic lines.
WORLDWIDE INSTALLATIONS
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