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EASL 2023 Abstract Highlights
6
Mins
August 2023
The following selected abstracts were the pinnacle of those showcased at the European Association for the Study of the Liver (EASL)…
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6
Mins
3rd August 2023
EASL 2023 Abstract Highlights
The following selected abstracts were the pinnacle of those showcased at the European Association for the Study of the Liver (EASL)…
1
Mins
4th August 2022
Prescription Event Monitoring of Checkpoint Inhibitor-Induced Liver Injury and Outcomes of Rechallenge: A 10-Year Experience
The definition and severity of checkpoint inhibitor-induced liver injury (ChILI) have been reported using the Common Terminology Criteria for Adverse Events (CTCAE) used in cancer therapy.
2
Mins
4th August 2022
Management of Severe, Steroid-Resistant and Steroid-Refractory Hepatotoxicity in Patients Treated with Checkpoint Inhibitor Immunotherapy
Checkpoint inhibitor immunotherapy (ICI) has revolutionised cancer care but is associated with immune-related toxicities, which may require ICI discontinuation and immunosuppressive therapies (IST).
1
Mins
4th August 2022
Pre-transplant Changes in Serum Protein Glycosylation Relates to Risk of Hepatocellular Carcinoma Recurrence After Liver Transplantation and Provide a Potential Prognostic Biomarker: A Proof-of-Concept Study
Hepatocellular carcinoma (HCC) recurs after liver transplantation (LT) in approximately 10% of patients. Changes in protein glycosylation have been described during the development of HCC and are associated with progressive disease and early mortality.
1
Mins
5th August 2021
Prevalence and Prognostic Value of Cirrhotic Cardiomyopathy as Defined According with the Proposed New Classification
The prevalence and prognostic relevance of cirrhotic cardiomyopathy (CCM), as defined according with the new core criteria proposed in 2019…
1
Mins
5th August 2021
Referral of Patients with Non-alcoholic Fatty Liver Disease with Significant Fibrosis from Primary Care to Secondary Care in Belgium
Non-alcoholic fatty liver disease (NAFLD) is becoming the most frequent cause of chronic liver disease worldwide. The stage of fibrosis…
1
Mins
5th August 2021
MicroRNA-27a-3p Modulates FoxO1 to Induce Tumour-Like Phenotypes in Bile Ducts
The authors analyse the miR landscape of CCA and non-malignant livers to define their roles in orchestrating gene regulation and promoting CCA development.
2
Mins
5th August 2021
A MET-Agonistic Antibody Mimicking Hepatocyte Growth Factor Accelerates Liver Regeneration and Improves Survival in Mice Undergoing Carbon Tetrachloride Exposure and Partial Hepatectomy
Small-for-size syndrome (SFSS) is defined by prolonged cholestasis, coagulopathy, and ascites within the first week of liver…
2
Mins
13th October 2020
Diagnostic and Prognostic Role of Presepsin in Patients with Cirrhosis and Bacterial Infection
Bacterial infection (BI) is a common event in the natural history of cirrhosis, often requiring hospitalisation due to hepatic and extra-hepatic organ dysfunction..
1
Mins
13th October 2020
Fibrosis-4 Score for Assessment of Liver Fibrosis is Useful in General Practice
Early recognition of liver fibrosis will be a challenge that continues in the coming years and should be performed by general practitioners (GP)…
1
Mins
13th October 2020
FIB-4 and APRI Scores Revalidation in a Cohort Study of 69,106 Chronic Hepatitis C Patients
Assessment of liver fibrosis is vital for enabling therapeutic decisions and prognostic evaluation of chronic hepatitis…
1
Mins
13th October 2020
Progress in Hepatitis C Testing as Part of the Hepatitis C Elimination Programme in Georgia
In April 2015, the country of Georgia, with a high prevalence of hepatitis C virus (HCV) infection (5.4% of the adult population, approximately 150,000 persons), embarked on the world’s first national HCV Elimination programme…
1
Mins
13th October 2020
Multivariant Surface Quasispecies in a Hepatitis B Virus Chronically Infected Individual with Concomitant and Continually Positive Surface Antigen and Anti-Hbs Biomarkers
Coexistence of hepatitis B virus (HBV) surface antigen (HBsAg) and antibodies (anti-HBs) can be found in 2.3–5.2% of chronic HBV (CHB) infected individuals…
1
Mins
13th October 2020
Contrast-Enhanced Ultrasound Algorithms for the Noninvasive Diagnosis of Hepatocellular Carcinoma in High-Risk Patients - A Prospective Multicentre Study (DEGUM CEUS HCC Trial)
Hepatocellular carcinoma (HCC) can be diagnosed noninvasively in high-risk patients by means of contrast-enhanced imaging…
1
Mins
28th May 2019
The Role of Adipose Tissue in Metabolic and Cardiovascular Complications After Liver Transplantation
Metabolic and cardiovascular complications are an important burden in patients after liver transplantation (LT) for many reasons, including as a result…
1
Mins
28th May 2019
Efficacy of Oral Thrombopoietin Receptor Agonist Lusutrombopag in Chronic Liver Disease by Underlying Disease Aetiology
Among patients with chronic liver disease (CLD), thrombocytopenia (TCP) is a frequent complication.1,2 Before invasive procedures and surgery in CLD…
2
Mins
28th May 2019
A Comparison of Currently Available Direct-Acting Antiviral Hepatitis C Virus Therapy in Canada: On the Path to Elimination
As many as 250,000 Canadians are living with hepatitis C virus (HCV) infection,1 and specific populations, such as people who use drugs (PWUD)…
2
Mins
28th May 2019
The NIACE Score: A Prognostic Indicator in Hepatocellular Carcinoma
The NIACE score is an easy-to-calculate prognostic score, and this study demonstrated that NIACE can distinguish between two subgroups with different…
2
Mins
28th May 2019
L-carnitine Could Be Beneficial in Nonalcoholic Fatty Liver Disease Patients by Improving Choline Metabolism and Reducing Liver Biomarkers
This study investigated what effect L-carnitine supplementation could have on liver metabolites. In this study, the authors hypothesised that L-carnitine…
3
Mins
28th May 2019
miRNA-21 Ablation in Mice Protects Against Gut Microbiota Dysbiosis During Cholestasis
Gut microbiota play an important role in gut–liver axis homeostasis. The understanding of the gut–liver relationship is crucial for the advances of…
1
Mins
28th May 2019
The Good Use of Paracetamol: Prospective Assessment of the Knowledge of Prescribers, Pharmacists, Care Providers, and Students in a University Medical Centre
The knowledge regarding the proper use of paracetamol is insufficient for the maximum chronic dosage, the risk of paracetamol hepatotoxicity…
2
Mins
28th May 2019
Neutrophil-to-Lymphocyte Ratio and Corticosteroid Response in Alcoholic Hepatitis
Treatment of alcoholic hepatitis with corticosteroids remains controversial, with recent studies indicating only a 28-day survival benefit…
1
Mins
31st May 2018
Resolution of Ascites, Hepatic Encephalopathy, and Variceal Bleeding in Patients with Hepatitis C Virus and Decompensated Cirrhosis Who Received All-Oral Direct-Acting Antiviral Treatment
Worldwide, 185 million people are infected with the hepatitis C virus (HCV);1 approximately 12% of these individuals have manifestations of decompensated…
1
Mins
31st May 2018
A Comparison of Renal Function Before and After Treatment of Chronic Hepatitis C Infection in Patients Who Achieve Sustained Virological Response with Direct-Acting Antivirals
Approximately 3 million people have chronic hepatitis C virus (HCV) infection in the USA. However, there are limited data with regard to the effect of…
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