Did you Miss any of AMRI's Causal Nexus Webinars?
AMRI hosts a weekly cadence of webinars that allows great minds to come together to learn more about the ideas, topics, and trends that are driving the CDMO industry.
This holiday season, AMRI would like to present you with all of the webinar recordings "wrapped up in a bow." All of the recordings can be found below and can be accessed at any time.
Episode One: Formulation Development and Clinical Supply of Aseptic Liposomal Formulations
- Iain MacGilp, Ph.D., Director, GMP Production, AMRI
- Amber McFarlane, Head of Formulation Development
- The importance of an integrated formulation development and clinical supply function that can support accelerated timelines to clinic, including complex formulations
- Recent and ongoing experiences in liposomal formulations, with focus on high pressure homogenization
- Linearity of laboratory to clinical supply scale-up with supporting analytics
- Broad applicability to variety of product types and presentations (liquid, lyophilized, potent compounds, cytotoxics
Episode Two: T3P® - A Versatile Peptide Coupling and Water Removal Reagent
- Peter Talbiersky, Ph.D., Manager of Fine Chemicals Sales, AMRI
- The importance of a green and versatile condensation reagent
- Safe alternative for commonly used condensation reagents like dicyclohexyl carbodiimide (DCC)
- Examples showing the advantages of T3P vs commonly used coupling agent
Episode Three: Sterile Drug Product Manufacturing During a Global Pandemic
- Ankit Agrawal, Senior Director, Commercial Strategy, AMRI
- Anish Parikh, Vice President, Drug Product Sales & Marketing, AMRI
- The shortage of sterile manufacturing capacity within CDMOs given the Covid-19 pandemic
- The push to keep manufacturing within US borders
- The immense coordination to work with our clients to find a vaccine for Covid-19
- The shortage of supplies (components, gowning, etc.)
Episode Four: Strategies for HPAPI Containment to Enable Rapid Development and Production
- Brian Haney, Ph.D., Director of Technical Operations, AMRI,
- Iain MacGilp, Ph.D., Director, GMP Production, AMRI
- The basics of handling HPAPI's safely in GMP production settings
- The traditional paradigms of engineering controls
- How new strategies of single-use containment can speed production process without compromising safety
Episode Five: Saving Time in Hit-to-Lead Investigations
- Mark Wolf, Ph.D., Section Head, Medicinal Chemistry - AMRI
- Doug Kitchen, Ph.D., Section Head, CADD, Medicinal Chemistry - AMRI
- The importance of a strong hit-to-lead program in drug discovery
- What makes a promising starting point
- Strategies used to triage hits
Episode Six: Biocatalysts, Biosynthesis, and Fermentation - The Evolution of Chemistry via Biology
- Pete Michels, Ph.D., Head of Global Fermentation, AMRI
- Jose Luis Barredo, Ph.D., Director, Engineering Services, AMRI
- A brief history of biocatalysis with a look at its current and future growth trends
- Role of practical process development for synthetic biology, fermentation, and biocatalysis
- Case studies demonstrating industrial applications of synthetic biology and biocatalysis
- cGMP and regulatory issues to consider for fermentation and biocatalysis
- The value of a multi-disciplinary teams in development