Workshop Description

This two-day, in-person hands-on workshop for faculty at any level in public and private academic institutions, will cover major concepts, methods and tools of translational bioinformatics and hands-on computer based exercises utilizing web-based bioinformatics resources - such as Georgetown Database of Cancer (G-DOC)- a unique translational research platform for connecting molecular and clinical data, the Universal Protein Resource, UniProt, and TCGA. Additional hands-on experience will be provided on systems biology level analysis of experimental multi-omics biomarkers discovery using pathway analysis tools.

Workshop Objectives

By the end of the workshop, participants will be able to

• Understand current data generation technologies used in translational research
• Identify which tools and/or resources to use to perform specific bioinformatics analysis related to translational research
• Perform basic systems level analysis of large-scale multi-omics data

Targeted Audience/Registration

The course is open to faculty at any level in public and private academic institutions.

Thanks to an R25 NIH grant, there are no registration fees. Because space will be limited to 20 participants, applications to join the course will be accepted till Wednesday September 6, 2017, 5pm EST. Applicants will be notified about acceptance to the workshop no later than Monday September 11, 2017.

Travel Awards

Thanks to an R25 NIH grant, travel awards that fully cover all attendance costs (Travel cost, accommodations, and meals) are available to faculty members in US under-resourced institutions. Please indicate your interest to apply for travel awards when you fill your online application form. Notification about travel awards will be communicated to applicants no later than Monday September 11, 2017.

Prerequisites

Participants are highly encouraged to complete our Massive Open Online Course (MOOC) “Demystifying Biomedical Big Data: A User’s Guide” prior to the workshop. This free online course is available on edX: https://www.edx.org/course/demystifying-biomedical-big-data-users-georgetownx-biox-201-01x-0

Use of computers

Computer workstations are provided; participants can bring their own wireless laptop if they wish (not required).

Workshop Topics

1. Introduction: Informatics platforms
2. BIG Data and Translational Bioinformatics
3. Gene Expression Analysis I with G-DOC applications (Hands-On)
4. Gene Expression Analysis II (microRNA profiling) with G-DOC applications (Hands-On)
5. Next Generation Sequencing: Exom-seq, ChIP-seq and RNA-seq applications (Hands-On)
6. Protein-Protein Interaction networks (Interactome) (Hands-On)
7. Bioinformatics of Genetics (SNPs & variations) (phenotypes & Diseases) (Hands-On)
8. Pathway analysis I (Hands-On)
9. Pathway analysis II (Hands-On)
10. Gene Network analysis (Hands-On)

Workshop Faculty

Dr. Bassem Haddad: https://www.edx.org/bio/bassem-r-haddad-md

Dr. Yuriy Gusev: https://www.edx.org/bio/yuriy-gusev-phd

Dr. Peter McGarvey: https://www.edx.org/bio/peter-mcgarvey-phd

Contact Information

For questions, please contact Dr. Yuriy Gusev