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Structural basis of pH-dependent client binding by ERp44, a key ...
www.ncbi.nlm.nih.gov › PMC5402435
Apr 3, 2017 · The pH-Dependent Enthalpy-Driven Interactions Between ERp44 and Ero1α. ... To further probe the electrostatic interaction between ERp44 and Ero1α, ...
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While pH-dependent reactivities involving thiolates as nucleophiles at close to physiological pH are usually higher for those thiols with the lower thiol ...
The pH-dependent properties are mediated by electrostatic interactions involving histidine residues, which are more favorable for the protonated form of ...
We propose the following mechanism for pH-dependent. IgG binding by FcRn (Figure 3d). At pH 8, most solvent- exposed histidine residues will be deprotonated ...
We have shown that pH-dependent binding of agonists is closely correlated with measurements of ligand efficacy at the 5-HT2A receptor. In general, efficacy ...
Apr 27, 2020 · The thiol-disulfide exchange reaction is of ... pH-dependent disulfide nanochemistry. The ... To circumvent electrostatic repulsion between primary ...
The pH-dependent binding of WT and “trigger” mutant chan- nel peptides to fluorescently tagged and anionic large unila- mellar vesicles (LUVs) was ...
May 3, 2021 · Anthrax toxin receptors act as mol. clamps or switches that control anthrax toxin entry, pH-dependent pore formation, and translocation of ...
Nov 20, 2018 · An additional study by Dyson and co-workers examined the pH-dependent behavior of Trx (Dyson et al., 1991, 1994). The authors showed that in ...
Chemical degradation was characterized by a pH-dependent increase of deamidation impurities while physical degradation was mainly attributed to dimerization, ...